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Comparative study of serum Gamma Glutamyl Transferase (GGT) in Impaired Glucose tolerance (IGT) and type 2 Diabetes Mellitus patients (DM)

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Universal Book Number 015-A94510112054

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Osheke Shekins Okere, Samuel Omolabi Adeyemo, Moses Dele Adams and Joshua Omoniyi Kolawole Abioye are conferred with Max Planck Research Award-2015 in Food Science

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Mohammed H F Shalayel*, Amar B Elhussein, Omar E Fadlelseed, Ahmed E A Abdelgadeir, Ashraf Naeem, and Osman M Elsheikh receive Ronald Ross Award-2014 in Biochemistry

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International Journal of Biochemistry deals in Biochemistry, Molecular biology, Cell, Biotechnology, Biophysical chemistry, Gene Gene structure expression, Gene mapping, Nucleosome Structure, DNA replication, Protein biosynthesis, Protein folding, Protein methods, Membrane, structure, Biochemical techniques, Bioenergetics, Bioinformatics , Immunochemistry, Transcriptome , Post-transcriptional , modification ,Southern blot, Western blot, Northern blot, Beta oxidation, Alpha oxidation, , Metabolomics, Transcriptome, Nanobiotechnology, Bioinformatics, Toxicology, Physiology, Pharmacology, Pharmacogenomics,Phytochemistry, Glycosylation, Laboratory Tests, Therapy, Disease surveillance, Tissue engineering, Protein engineering,Genetic engineering, Systems biology, Forensic science, Nutraceutical, Biofuel, Environmental engineering, Enzyme engineering, Biotransformation, Downstream processing, and Signal transduction Biophysics Biomolecule DNA Membrane biophysics Nerve Bioelectrical 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anaerobic glycolysis fructose galactose dihydroxyacetone phosphate aerobic anaerobic cytosol hydrogen phosphate adenosine diphosphate fermentations ethanol lactic acid aerobic respiration substrate-level phosphorylation phosphorolysis isozyme glucokinase fructose 6-phosphate glucose phosphate isomerase Phosphofructokinase 1 pyrophosphate-dependent phosphofructokinase glyceraldehyde 3-phosphate Triosephosphate isomerase glyceraldehyde 3-phosphate dehydrogenated inorganic phosphate 1,3-bisphosphoglycerate Phosphoglycerate mutase 2-phosphoglycerate phosphoenolpyruvate pyruvate kinase erythrocytes NAD+ NADH hexokinase triglycerides homeostasis acetyl-CoA citrate ATP citrate lyase fatty acid synthesis hypoglycemia AMP fructose 2,6-bisphosphate glucagon PFK2 protein kinase A epinephrine lactate conjugate base lactic acid fermentation bacteria yogurt ethanol fermentation mitochondria pyruvate decarboxylation oxidative phosphorylation Pyruvate kinase deficiency tumor Warburg hypothesis radioactive 3- phosphoglycerate carbohydrate catabolism DNA replication biological inheritance semiconservative replication proofreading genome DNA polymerase polymerase chain reaction deoxyribose cytosine guanine thymine hydrogen bonds phosphodiester bonds high energy phosphate nucleoside triphosphates pyrophosphate Prokaryotic DNA replication Eukaryotic DNA replication DnaA origin recognition complex pre-replication complex hydroxyl viruses adenoviruses circoviruses geminiviruses parvoviruses RNase DnaG RNA recognition motif DNA Pol III nick translation replication fork theta structure prokaryotes Okazaki fragments DNA ligase flap endonuclease DNA gyrase supercoils secondary structures single-strand binding proteins Clamp proteins replisome DNA Helicase DNA clamp Single-Strand Binding (SSB) Proteins Topoisomerase Primase Telomerase eukaryotic chromosomes germ cell telomere somatic cells Ter protein Tus protein D-loop replication Beta oxidation citric acid cycle FADH2 electron 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Association Between Lactate Dehyroganse And Liver Enzymes With Renal Markers In Chronic Renal Failure

Prof. Jansi Rani a , Dr. Lenin a , Dr. Hemavathy. R b , Dr. Abirami Soundararajan c , Dr. Rhutheshmohavanam d , S. Thanmayaananth e

a Department of Biochemistry Sri Lakshmi Narayana Institute Of Medical Science Puducherry, India b Department of Physiology Vellore Medical college and Hospital Vellore, India

c Uthangarai General Hospital Krisnagiri District Tamil Nadu, India

d Venkateshwara Dental College, India

e Pondicherry Institute of Medical Sciences Pondicherry, India

Article history:

Received: 14 December, 2020

Accepted: 14 December, 2020

Available Online: 10 February, 2022

Corresponding Author: Prof. Jansi Rani* Professor Department of Biochemistry Sri Lakshmi Narayana Institute Of Medical Science Puducherry

Dr. Lenin Assistant Professor

Dr. Hemavathy. R Assistant Professor

Dr. Abirami Soundararajan Medical Officer

Dr. Rhutheshmohavanam Dental Surgeon

Abstract

Introduction: The prevalence of chronic kidney disease (CKD) is estimated to be 8-16% worldwide. With an aging population, and rising levels of hypertension, diabetes and obesity, renal diseases pose an increasing burden on public healthcare. Two million people worldwide are currently on renal replacement therapy (RRT), dialysis or have a renal transplant. Materials and Methods: 250 dialysis patients of age group between 30- 70 years of both genders were selected for the study. A total of 4ml venous blood was collected from the patients 3ml in a plain tube, 1ml in EDTA Result: In this present study was showed lactate dehydorgenase enzyme was associated with potassium. There was no association between lactate dehydrogenase and others makers such as ALB, urea, creatinine, sodium and chloride. Conclusion: Lactate dehydrogenase levels were found to be positive correlation with potassium. In this present study was shows there was no correlation between lactate dehydrogense and liver and renal markers in chronic renal failure. Keywords: Lactate Dehyrogenase, Chronic Renal Failure, Renal Markers, Liver Enzymes

Citation:

Prof. Jansi Rani, Dr. Lenin, Dr. Hemavathy. R, Dr. Abirami Soundararajan, Dr. Rhutheshmohavanam, S. Thanmayaananth, 2022. Association Between Lactate Dehyroganse And Liver Enzymes With Renal Markers In Chronic Renal Failure. International Journal of Biochemistry. Photon 202, 559-564 Photon

Photon Ignitor: ISJN44385728D912410022022

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Evaluation of MPV & calcium as a prognostic marker in type 2 diabetes

Miss Manzura Rustum Mulani a*, Mrs. Veena S. Hatolkarb

a JIIU’s IIMS&R medical college, warudi. 431202, Badnapur, Jalna. Biochemistry, Maharashtra, India

b MGM Medical college, Aurangabad, Maharashtra, India

Keywords:

diabetes mellitus, Mean platelet volume and calcium

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Hordegen P., Hertzberg H., Heilmann J., Langhans W., Maurer V., 2003. The anthelmintic efficacy of five plant products against gastrointestinal trichostrongylids in artificially infected lambs. Veterinary Parasitology 117(3), 51–60.

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Log TG / HDL-C ratio in type-2 diabetes mellitus

Dr. Manzura R. Mulani^a* , Dr. Veena S. Hatolkar^a , Dr. Nitmala R. Hajari^b

^a IIMSR medical college and Noor Hospital, Warudi, Maharashtra, India

^b GMC Aurangabad, Maharashtra, India

Article history: Received: 04 February, 2021 Accepted: 23 March, 2021 Available Online: 18 April, 2021

Corresponding Author: Dr. Manzura R. Mulani

Citation:

Dr. Manzura R. Mulani, Dr. Veena S. Hatolkar, Dr. Nitmala R. Hajari, 2021. Log TG / HDL-C ratio in type-2 diabetes mellitus. International Journal of Biochemistry. Photon 201, 554-558

Photon Ignitor: ISJN44385728D912118042021

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Abstract

T2DM is associated with atherogenic dyslipidemia (AD), defined as decreased HDL-C plus raised triglycerides (TG). AD confers increased risk for CAD, even when LDL-C is at target. AD is rarely assessed due to lack of screening methods consensus. To establish the prevalence and severity of AD from log(TG)/HDL-C in T2DM males, and to determine how it relates to cardio metabolic phenotype, glucose homeostasis, micro- and macrovascular complications. So, The aim of present study was to evaluate the log (TG)/HDL-C ratio as AD markers and non HDL-C as measurable predictors of CVD in T2DM. 55 T2DM divided according to quintiles (Q) of log(TG)/HDL-C. AD prevalence defined as HDL-C <40 mg.dL-1 plus TG ≥150 mg.dL-1. Mean HDL-C and TG were 35.38±9.53 and 170.11±84.96 mg.dL-1. AD prevalence was 47%. AD correlated with lower β-cell function, with accelerated loss of insulin secretion, and with poorer HbA1c levels. AD was related to a high prevalence of CAD, and also to 10-year absolute CAD risk. log (TG)/HDL-C is a simple means to estimate AD and the residual CV risk it confers in T2DM. AD closely associates with major cardio metabolic and glucose homeostasis determinants and poorer metabolic control. The ratio also relates to macroangiopathy prevalence and ranks future CAD risk, and is well-suited to capture non-LDL-related macrovascular residual risk and major glycemic determinants

Diabetes mellitus (DM) is a global pandemic. Increase in incidence of DM is a major health concern and now a global health priority. As such it is genetically & clinically heterogeneous disease requiring continuous follow-up. DM is characterized by enhanced platelet activation & coagulation proteins and reduced fibrinolytic activity. This prothrombotic state and reduced fibrinolytic activity. This prothrombotic state precedes the development of cardiovascular disease (CVD). The aim of this study was to evaluate the serum levels of mean platelet volume (MPV) & calcium in type 2 diabetic patients. The study group comprised of 50 type 2 diabetic patients visiting medicine Out Patient Department of MGM institute of medical college and hospital, Aurangabad, Maharashtra, 50 age and sex matched healthy participates comprised the control group. The study found that MPV and calcium levels were significantly high in type 2 diabetes compared the control group significantly positive correlation between MPV with FBSL, HbA1c & platelet count was noted. Calcium appears to play important roles in both insulin secretion and action. The study shows that the patients with DM had increased MPV& Ca2+which may predispose for the development and progression of diabetic complications.

Proline: The Plant Protectant

Kalpna Bhandari*

Laboratory of Plant Physiology and Biotechnology, University Department of Botany, Ranchi University, Ranchi-834008, India

^a Centre for Conservation and Utilization of Blue Green Algae, Indian Agricultural Research Institute, New Delhi-110012, India

^b Department of Microbiology, Kurukshetra University Kurukshetra, Haryana, Meerut, 136119, India

All Rights Reserved with Photon. Photon Ignitor: ISJN44385728D814915062017

Gastro protective activity and antioxidant enzymatic studies of Maytenus emarginata (Willd.) Ding Hou of South Indian forest

Dhanasree Basipogu*^a, Nizamuddin Basha Syed^b

^a Assistant Professor, Dept. of Biochemistry, KVR Govt. College (w), Kurnool, A.P., India

^b Dept. of Biochemistry, Sri Krishnadevaraya University, Anantapur, A.P. India

Keywords:

M. emarginata, Gastro protection, GSH, GR, GPx, GST, SOD, CAT

Effect of Deltamethrin on Some Biochemical Metabolites in Clarias lazara (juveniles)

Inyang I.R.^a*, Pughikumo D.T.^b, Omu A.O.^a

a Aquatic toxicology unit, department of biological sciences, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria

b Department of Physiology, College of health sciences, Niger Delta University, Wilberforce Island, Bayelsa State Nigeria

^bDepartment of Biotechnology, B. V. B. College of Engineering and Technology, Vidyanagar,Hubli- 580031, Karnataka, India

Urinary Alkaline Phosphatase, Gamma Glutamyl Transferase and Lactate Dehydrogenase in Type 2 Diabetic Nephropathy, and their Correlation with Albuminuria

Laxman Pokhrel, Mohamed Rafi, Shivashankara A.R., Avinash S.S., Arun Kumar K., Malathi M.

Effect of smoking, alcoholism and non-vegetarian diet on lipid profile in non-diabetic, non-hypertensive myocardial infarction patients

Effects of nitrate, phosphate and salinity stress on cell division, chloroplast morphology and cell wall architecture in a filamentous green alga Spirogyra punctulata Jao

Gour Gopal Satpati, Ruma Pal*

Keywords:

Cell wall, chloroplast, light microscopy, scanning electron microscopy, stress

Photon Ignitor: ISJN44385728D687730052014

Cyperus rotundus delays diabetic cataract better than Cyamopsis tetragonolobus by regulating polyol pathway and oxidative stress in Wistar albino rats

Vijayalakshmi Krishnamoorthy^*, Seema Surendran

Keywords: Cyperus rotundus, Cyamopsis tetragonolobus, Diabetic cataract, Polyol pathway, Oxidative stress, Antioxidant, Cataractogenesis

Photon Ignitor: ISJN44385728D701106082014

Correlation of serum lead with various hematological parameters in male humans (car painters) of Lahore

Fozan Ahmad, Ayesha Pervez, Fahmida Khatoon*, Zamir Ahmed, Sadia Mahmood

Photon Ignitor: ISJN44385728D664120032014

A comparative evaluation of CK- MB and Cardiac Troponin - I as an early diagnostic biomarker for the diagnosis of acute myocardial infarction (AMI)

Preeti Pachpute*, Z.G. Badade, A.D. Deepak, S.R. Pachpute

Thomas Edison Award-2014

Keywords:

Myocardial infarction, cardiac Troponin I, CK-MB

Photon Ignitor: ISJN44385728D634822032014

Role of LCAT activity and HDL cholesterol levels in reduction of reverse cholesterol transport in newly detected type 2 Diabetes Mellitus

Shashikant Nikam*, Suman Doddamani, Padmaja Nikam, Archana Dambal, Ramaiah

Application of Immobilized Mushroom Polyphenoloxidase for the Removal of Phenol and 4-Chlorophenol

V.A. Edalli and C.M. Kamanavalli*

The wound healing activities of Garcinia hydroxylbiflavanonol (GB1) from Garcinia kola in streptozotocin-induced diabetic rats

Nwaehujor C.O.*, Nwinyi F.C., Igile G.O.

Blood and salivaryoxidant - antioxidant status in chronic periodontitis: A correlative study

Roopa Sebastian*, ShivarajashankaraY.M., Manjula Shantaram, Shivashankara A.R.Dayakar M.M., Allwyn Joshua

Genotypes of Interleukin-1 Receptor Antagonist (IL-1RN) In Smokers from North India

Mukesh Pal Singh*, Shalendra Kumar Sharma, Sanjeev Babu Shukla, Nitin Prakash Pandit

A Comparative and Correlative Study of Sialic Acid, Malondialdehyde and Antioxidant Status in Blood and Saliva of Male Chronic Alcoholics

Susanna T.Y.*, Shivashankara A.R., Malathi M.

Serum ICAM-1 and Iron Concentrations can Predict the Response to Interferon Treatment in Egyptians Chronic Hepatitis C Patients

Amal A. Mohamed*, lamiaa Mobarak, Fatheya AL-Halwany, Gamal A. Singer, Seham Mohmoud, Dalia Ghourab, Zeinab Mostafa

Evaluation of alternative chemotherapeutic agent from Ruellia tuberosa for hepatocellular carcinoma using HepG2 cell lines

B Arirudran, Vijayalakshmi Krishnamurthy*, A Saraswathy

Salivary flow rate, enzymes, total protein and antioxidant status as biomarkers of oral cancer, and a correlative study of enzymes and antioxidants in blood and saliva

Arnadi Ramachandrayya Shivashankara*, Smyrna Martyr S., Toni Thomas, Ashwin DA Lobo,

Manjeshwar Shrinath Baliga

Injectable progestin contraceptive could increase the risk of insulin resistance syndrome in humans

Onyesom Innocent, Ogbodu, D. Ejiroghene* Osioma, Ejovi Avwioroko, J. Oghenetega

Lipid profile and liver marker enzymes in male and female culturedadults Clarias gariepinus

Hammed A.M., Wusu A.D., Amosu A.O.*, Fashina-Bombata H.A., Avoseh O.

Assessment of Smad-1 and Spondin-2 as biomarkers for early detection of Nephropathy in type 2 Diabetic patients

Ibrahim A. Emara*, Mohamed S. Shouman

Arsenic induced apoptosis in C57Bl/6 mice

Dalal Basudeb*

A correlative study of copper, ceruloplasmin and iron in urine as biomarkers for diabetic nephropathy

Ramlinga Reddy, Paul Simon, Arnadi Ramachandrayya Shivashankara*

Inhibition of DNA relaxases by Elores to control spreading of resistant gene through conjugation

Manu Chaudhary, Anurag Payasi*

Purification and characterization of fibrinolytic enzyme from Kiwifruit

Salem A. Habib, Entsar A. Saad*

Purification, characterization and potential uses of Fish Lipase: A Review

Prasidhi Tyagi, Neelima Boora, Kameshwar Sharma Y.V.R.*

Comparative study of EM and IMO manure on the growth of carrot (Daucus carota L.) and biochemical analysis

Mbouobda Hermann Desire(a)*, Fotso(a), Margaret A. Tita(a), Rosaline F. Muyang(b), Dominik K.

Njualem(c), Denis N. Omokolo(d)

Influence of subculturing on in vitro shoot proliferation of Dioscorea hispida: source of many dietary minerals

Susmita Shukla(a)*, S.K. Shukla(b)

Toxic and anti-fertility effects of Alocasia macrorrhiza and Calotropis procera ethanolic extracts on male mice

El-Shahat A. Toson, Salem A. Habib, Entsar A. Saad*, Nahla H. Harraz

Correlation of spot urine protein creatinine ratio with twenty four urine protein and serum lipid profile in type 2 diabetic nephropathy patients

Anitha Maria Thattil, Arnadi Ramachandrayya Shivashankara*, Ramlinga Reddy

Fluorescent analysis of catecholamines and histamine in plant single cells

Victoria V. Roshchina*, V.A. Yashin, A.V. Kuchin, V.I. Kulakov

Evaluation of HbA1c, Fasting insulin and Lipid profile in the assessment of Diabetic Nephropathyin Type 2 diabetes Mellitus in Males: A rural Hospital Study

Munilakshmi U.*, Shashidhar K.N., Harish R., Madhavi Reddy., Lakshmaiah V.

Determination of the proximate composition, vitamins,minerals and anti-nutrient contents ofGuava (Psidium guajava) seed

Fowomola M.A.*, AdesinaS.R., Adebayo F.O.

Effect of 2,4- dichlorophenoxyacetic acid on some selected haematological and biochemical parameters in Clarias gariepinus

I.R Inyang*, E.N. Ogambab, O. Inerepamo

Erosive effect of sports drinks on tooth enamelFathilah Abdul Razak*, Nurul Salwa Che Abdul Rahim, Sheril Nur Aida Rosli, Sharifah Norul Akmar Syed Zamri

A comparative study of bone related biochemical markers in postmenopausal women with and without diabetes mellitus

Esha Mati*, K.N. Shashidhar, B.N Raghavendr Prasad, N.S Gudia, Harish R.

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Graphical Abstract: Nodalex-plants of D. hispida showing budbreak after 5 days of inoculation

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